aurisco pharmaceutical co., ltd.-凯发app下载

chiral synthesis

we offer custom synthesis of chiral molecules through separation of racemic material as well as modern asymmetric synthesis.

  • asymmetric induction
  • chiral pool
  • organocatalysis
  • enzymatic reactions (reductions, esterases, decarboxylases)
  • single and double stereo-differentiating reactions
  • desymmetrization


we’ve developed significant expertise in fermentation to produce apis, intermediates and biocatalysts.

  • expert inhouse biotechnology team
  • close collaboration of biotechnology department with chemistry department
  • approx. 300m² commercial fermentation workshop, from 50l to 23,000l fermenters

synthetic biology

our protein expression platform has established four recombinant expression systems from prokaryotic (e.coli, bacillus) to eukaryotic (yeast, brassica napus(plantcell system)).capabilities:

  • 2,400 m2 biocatalysis labs that can handle 5-10 projects simultaneously
  • a large in-house library including 2000 enzymes from commercially available sources enabling rapid screening

our integrity synthetic biology platform offers a one-stop solution:

  • contract research of protein/peptide expression
  • peptide development and manufacturing
  • api industrial strain development
  • biocatalysis development, replacing chemical process with enzyme technology


  • photochemistry provides with green, high efficiency, low pollution benefits;
  • we are manufacturing apis in ton scale by using photochemistry technology.

polymorph and salt

  • discovery of new polymorph, crystallization process development and optimization.
  • milling and micronization:equipped with different milling device, can meet with different psd requests.

oligonucleotide development

  • aurisco has an integrated oligonucleotides process development and manufacturing platform from preclinical to commercial. we support the development and manufacturing of a variety of oligonucleotide modalities including dna, rna, morpholino oligonucleotide (pmo), and etc.

analytical services

  • ipc and release methods development and validation for small and large molecules
  • api and drug product release testing ich stability studies
  • reference standard characterization and qualification
  • potential genotoxic impurities (pgi) method development, validation and testing
  • impurity/degradant isolation and structure elucidation
  • oligonucleotide and peptide analysis
  • physical property characterization
  • microbial testing

key analytical technologies

  • chromatography: uplc, hplc, ic, gc
  • mass spectrometry: lc-ms, lc/ms/ms,gc-ms, uplc-uv-ms, uhplc-qtof
  • solid state characterization: xrpd, dsc, tga , psd
  • identification: nmr
  • general testing: kf, uv-vis,
  • psd testing: malvern 2000,3000, sympack
  • elemental analyzer: icp-ms